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Longevity and cellular defence

Thymosin Alpha-1

Also known as Ta1, Thymalfasin

A 28-amino-acid peptide originally isolated from thymus tissue, studied for its role in immune regulation.

What it is

Thymosin Alpha-1 is a peptide first purified from thymosin fraction 5, an extract of the thymus gland. The thymus is where T cells mature, which is the origin of research interest in this peptide. It is approved for clinical use in a number of countries outside the United States under the name Thymalfasin.

What published research examines

  • T-cell maturation and function
  • Toll-like receptor signalling
  • Immune response in infectious disease research
  • Vaccine response in older adults

Where the research stands

Thymosin Alpha-1 has a substantial international clinical literature and is approved in several countries, though not by the FDA in the United States.

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