Repair and recovery
ARA-290
Also known as Cibinetide, pHBSP
An eleven-amino-acid peptide derived from erythropoietin, studied for tissue-protective signalling without erythropoietic activity.
What it is
ARA-290 is a short peptide modelled on a structural region of erythropoietin that is not involved in red blood cell production. Research interest centres on the innate repair receptor, a proposed receptor complex distinct from the classical erythropoietin receptor, which is why the compound is studied separately from EPO itself.
What published research examines
- Innate repair receptor signalling
- Small-fibre nerve density in clinical research cohorts
- Inflammatory and metabolic markers
- Separation of tissue-protective from erythropoietic effects
Where the research stands
ARA-290 has been through early-phase human trials, which is unusual for compounds in this catalogue, though the evidence base is still small and work is ongoing.