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Skin and connective tissue

AHK-Cu

Also known as Alanine-Histidine-Lysine copper, Copper tripeptide-2

A copper-binding tripeptide studied for effects on hair follicle cells and blood vessel formation.

What it is

AHK-Cu is a three-amino-acid sequence that binds copper, in the same broad family as GHK-Cu but with a different sequence and a distinct research profile. Copper-binding peptides are studied because the bound copper appears central to the activity observed, rather than the peptide acting alone.

What published research examines

  • Dermal papilla cell behaviour in culture
  • Angiogenic signalling and VEGF expression
  • Comparison with GHK-Cu, which shares the copper-binding property
  • Collagen and extracellular matrix markers

Where the research stands

The AHK-Cu literature is smaller than that for GHK-Cu, and a good deal of it comes from cosmetic-science research.

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